Driving Biological Projects

Driving Projects are research projects that are selected for their scientific merit in answering important biological questions and that represent a broad range of research endeavors, advancing their disciplines. Driving Projects stimulate the BiologicalNetworks project to improve its technologies and provide feedback on our work. How to become a Driving Project.

List of current and past Driving Projects (ordered by activity):


1. Transcriptional regulation database, (UCSD)

2. Brain Development study, (UCSD and Institute Pasteur / College de France, France)

3. Whole Genome Metabolic Reconstruction, (UCSD)

4. Senescence and apoptosis, (UPenn / The Wistar Institute, Philadelphia, PA)

5. Autism study, (UCSD and Institute Pasteur / College de France, France)

6. G protein-coupled receptors as novel targets for drug discovery in cancer, (The Scripps Research Institute, La Jolla, CA)

7. Integrative analysis of embryonic stem cells regulation by OCT4 family of mammalian transcription factors , (UCSD)

8. Drosophila melanogaster stem cells regulation by ESCARGOT transcription factor family, (SALK Institute, La Jolla, CA)

9. Gene regulatory Map of Asthma, (UCSD)

10. Host-pathogen interaction resource , (UCSD)

11. Human – Influenza interaction , (Institute of Health, Madrid, Spain)

12. Apoptosis in human lymphocytes , (Institute of Health, Madrid, Spain)

13. Reconstruction of Lactococcus garivieae metabolic and gene regulatory network, (Institute of Health, Madrid, Spain)

14. NF-kappaB signaling, (UCSD)

15. Pathway mapping of molecular off-targets for drug discovery, (UCSD)

16. Systems pharmacology tools for drug targets, off-target pathways discovery and safety biomarkers, (Q-Mol, LLC, San Diego, CA)

17. Metabolic Pathways mapping of microarray experimental data in buffalo and cow, (National Bureau of Animal Genetic Resources (NBAGR), India)

18. Human hypertension, (UCSD)

19. Brain Injury study, (University of Florida, Gainesville, FL)

20. Parasite studies (Life cycle of Giardia parasite), (UCSD, School of Medicine)

21. Microbial metabolism studies (Thermatoga metabolism), (Sanford-Burnham Medical Research Institute, La Jolla, CA)


Biological Articles: